Agios’ AG-221 racks up more cancer remissions, setting the stage for a pivotal challenge – FierceBiotech
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Just a few months after Agios Pharmaceuticals highlighted clear indications of success for its early-stage drug AG-221 for various blood cancers, the biotech has followed up with a bonus round of promising results at the annual scientific meeting of the American Society of Hematology. Investigators noted that a growing number of patients with IDH2-mutant positive malignancies have achieved a complete response, with the durability of the response extending out now to 8 months in some cases. And the clinical success is opening the door to a registration study now planned to launch in 2015.
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